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Rosacea, also known as couperose or facial erythrosis, can appear similar to acne. However it is not hormone-related, but instead probably reflects a genetic pre-disposition. The first stage is a reddening of the skin on the face, which intensifies in the heat or after drinking alcohol. This is followed by the appearance of inflamed pimples. Particularly severe cases may result in a bulbous nose, or rhinophyma.

The early stages of rosacea can often be controlled well with a cortisone-free cream. Pustules and papules in stage 2 of the condition respond to treatment with vitamin A acid or a fruit acid peel. Unwelcome red marks can be removed very successfully with Nd:Yag laser treatment. A rhinophyma can be reduced in size using a CO2 laser.